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recomBead EBV IgG 2.0
recomBead EBV IgM 2.0


Luminex®-based immunoassay (magnetic beads) using recombinant antigens for detection of IgG or IgM antibodies against Epstein-Barr Virus (EBV) in human serum or Plasma

The Epstein-Barr virus, an ubiquitously occurring herpes virus, can cause the symptoms of infectious mononucleosis (Pfeiffer´s disease) on primary infection. Moreover, as a result of the lifelong persistence of this pathogen, reactivations can occur, especially in immuno-incompetent persons.

Due to the diversity of symptoms caused by EBV infection and their correspondence with the symptoms of other diseases, a secure EBV diagnosis is of great relevance for differential diagnostics. One of the main tasks in routine diagnosis is therefore the serological differentiation of a primary infection from a past infection and the exclusion of an EBV infection.

Product advantages

  • Reliable screening of EBV by using recombinant Antigens:

    • safe detection of long past infections due to the very high specificity of the diagnostic EBV key antigen EBNA-1
    • safe detection of acute EBV infections already in the early phase due to the optimized antigen combination in the recomBead EBV IgG 2.0 and recomBead EBV IgM 2.0 test Systems

    • The modern Luminex® multiplex technology integrates the advantages from ELISA (screening) and strip (confirmation) assays:

      • fast and easy test procedure similar to ELISA
      • fully accomplished for high sample throughput
      • only one single test run provides information about the different stages of infection – due to simultanous and seperate detection of EBV specific antibodies

    • Safe results:

      • evaluation by integrated controls (incubation control, conjugate control, negative control) in each sample
      • fully automated processing, analysis and data transfer to the laboratory information system possible
      • CE label

Testprinciple and procedure

 

 

Relevant EBV antigens and recombinant analogs

Evaluation

Diagnostic Sensitivity

* Patients with past EBV infection and anti-EBNA-1 IgG antibodies
** Patients with acute EBV infection and anti-EBV IgM antibodies

Diagnostic Specificity

Storage

At +2°C - +8°C


Commercial product

Article number 4554recomBead EBV IgG 2.0
(Reagents for 96 determinations)
Article number 4555recomBead EBV IgM 2.0
(Reagents for 96 determinations)
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Additional Information
Available only in: Germany, Europe